The MPRE8 Multi-tube pre-heater (pictured) is an 8 tube pre-heater for either superfusion or for the inflow of a tissue chamber. It has a very small mixing volume at the tip (1-2microL) which allows rapid switching between solutions (<<1sec). Switching can be achieved using valves or using our cFlow 8 Ch Flow/switch Controller to operate pinch valves. The unique construction of the MPRE8 permits the use of a single thermistor sensor so that it is compatible with the TC2BIP and other controllers using a 10kohm thermistor sensor. Solution can also flow in multiple tubes for mixing applications. Flow rates up to 1ml/min can be used. The MPRE8 tip is has a unbreakable polyimide outlet tube with a 360microm inside diameter. The outlet tube length can be varied for different applications. The mixing tip can be removed and replaced if necessary. Custom tips can be used. Where valuable compounds are used the small dead volume in the tubes of theMPRE8 minimises the amount of drug wasted in the tubing. Also theMPRE8 can be used to heat and perfuse a region of a chamber where it impractical to heat the whole chamber.
The HPRE2 is a single channel inline heater for maintaining the temperature of the perfusate entering a tissue chamber. This unique design with 3 tubes side-by-side allowing countercurrent heat exchange allows us to make a compact and efficient heate with flow rates up to 3ml/min. There is also a new version HPRE2HF suitable for flow rates up to 6ml/min. Being constructed of glass and polycarbonate it allows the use of many drugs and compounds without contamination caused by stainless steel tubes