*近的研究表明,硫化氫(H2S)在生物醫(yī)學(xué)和生物方面有一個(gè)顯著的信號(hào)作用。尤其是在哺乳動(dòng)物心血管系統(tǒng)中產(chǎn)生硫化氫可導(dǎo)致血管擴(kuò)張、血壓降低。
在研究問(wèn)題中有一個(gè)相對(duì)較新的發(fā)現(xiàn),那就是在生物介質(zhì)的氣體信號(hào)分子中可以很**地測(cè)量H2S濃度。以前使用的*譜法和色譜法不僅受到明顯的干擾,而且還需要辛苦地做密集樣本的制備程序工作,這樣的制備程序工作會(huì)導(dǎo)致H2S在樣本中消失。
*近,由楊等人發(fā)表在科學(xué)雜志的的一項(xiàng)研究采用了獨(dú)特的方法來(lái)測(cè)量硫化氫濃度。論文題為“H2S作為生理舒張:高血壓小鼠胱硫醚-酶缺失”,利用了Lazar公司實(shí)驗(yàn)室,在洛杉磯公司開發(fā)了一種微型硫化氫電*。
這種獨(dú)特的電*是同類產(chǎn)品中*小的離子電*,可以測(cè)量低到10微升樣品,如96孔板。H2S可以測(cè)量到小于0.1微摩爾濃度(小于100納米的摩爾)的樣品。樣品制備簡(jiǎn)單,直接在96孔板或其他微量樣品容器中測(cè)量,從而*大程度減少H2S的流失以及提高測(cè)量精度。與其他方法不同的是,這種微電*測(cè)量方法沒(méi)有已知的干擾。
楊等人,科學(xué)雜志,“生理性舒張血管:高血壓小鼠胱硫醚-裂解酶的缺失”,科學(xué),322卷,5901號(hào),第587-590,2008(10月2008年 科學(xué)問(wèn)題)
該硫化氫(H2S)測(cè)試系統(tǒng)****的特點(diǎn):
1、測(cè)量小樣本??梢詼y(cè)量10微升的小樣本,如96孔板。
2、低檢測(cè)限。測(cè)量硫化氫濃度低至0.1微摩爾(100納米摩爾)。
3、樣本制備簡(jiǎn)單。直接在小樣本容器中制備樣本。
4、成本效益。比其他測(cè)量方法成本明顯省錢,如*譜法和色譜法。
5、直接與您的電腦或者筆記本連接。直接USB端口后測(cè)量、記錄和制圖直接在你的電腦上顯示。
6、沒(méi)有已知的干擾。不像*譜法和色譜法測(cè)量有已知的干擾。
每個(gè)ArrowH2S?測(cè)試系統(tǒng)執(zhí)行以下任務(wù):
1、測(cè)量:使用我們精致的離子分析器和和****的微型H2S離子電*。
2、記錄:我們****的軟件直接將測(cè)試詳細(xì)記錄在你的電腦上,以便你分析數(shù)據(jù)。
3、制圖:我們****的軟件可直接將你的數(shù)據(jù)制成圖表,這樣你就能很輕松的查看和分析數(shù)據(jù)。
英文原文:
ArrowH2S?
Complete Hydrogen Sulfide Measurement System
Measure, Log, and Graph all in one system
Selection of micro hydrogen sulfide systems available - skip ahead to hydrogen sulfide system listings
Recent studies have shown Hydrogen sulfide (H2S) to have a significant signaling role in biomedicine and biology. In particular, H2S, which is produced in the cardiovascular system of mammals, was found to lead to dilation of blood vessels and the lowering of blood pressure.
One of the problems in studying this relatively newly discovered gaseous signaling molecule is accurately measuring H2S concentration in biological media. Polarographic and chromatographic methods, which were previously used, not only suffer from significant interferences, but also require labor intensive sample prep procedures which can lead H2S loss from the sample.
A recent study by Yang* et al just published in SCIENCE uses a unique method to measure H2S concentration. The paper entitled "H2S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine -Lyase" uses a micro H2S electrode developed by LAZAR RESEARCH LABORATORIES, INC., Los Angeles, CA.
This unique electrode is the smallest ion electrode of its kind and can measure volumes down to 10 microliters in samples such as 96 well plates. H2S can be measured down to less than 0.1 Micro Molar concentration (less than 100 nano Molar). Sample prep is simple and done directly in the 96 well plate or other micro sample container thereby minimizing H2S loss and increasing accuracy. Unlike other methods, this micro electrode measurement method has no known interferences.
*Yang et al, Science, Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine -Lyase",Science, Vol. 322, No. 5901, pp. 587-590, 2008 (Science issue of 24 October 2008)
Unique features of the ArrowH2S? Hydrogen Sulfide Measurement System
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Measure micro samples- Measure samples as small as 10 microliters in samples such as 96 well plates
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Low detection limit- Measure H2S concentrations as low as 0.1 micro Molar (100 nano Molar)
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Simple sample prep- one step sample prep done directly in the micro sample container
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Cost effective- significant savings over other techniques such as chromatography and polarography
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Use directly with your PC or laptop- Connects directly to your USB port for logging, graphing, and data recording directly on your PC
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No known interferences unlike chromatography and polarography
Each ArrowH2S? system performs the following tasks:
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Measures - Measures H2S using our sophisticated ion analyzer and exclusive micro H2S ion electrode
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Logs - Our exclusive software records details about your measurements straight to your PC for easy analysis.
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Graphs - Our exclusive software charts your data onto a graph so you can easily view and compare data.
訂貨信息如下:
ArrowH2S? Micro Hydrogen Sulfide Measurement System
System includes micro H2S electrode, ion analyzer with digital output to your PC or laptop, and complete software program for monitoring, recording, and logging H2S concentration data.
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ISM-146H2S-XS
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ArrowH2S? Micro Hydrogen Sulfide Measurement System for NMR tubes
System includes micro H2S electrode with extra long stem for NMR tubes, ion analyzer with digital output to your PC or laptop, and complete software program for monitoring, recording, and logging H2S concentration data.
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ISM-146NMRH2S-XS
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Micro ArrowH2S? flow through measurement system
Micro flow through H2S electrode with micro flow cell with input and output ports, ion analyzer with digital output to your PC or laptop, and complete software program for monitoring, recording, and logging H2S concentration data.
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ISM-146FTH2S-XS
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