系統(tǒng)簡介:
biomomentum廠家Mach-1軟組織壓縮、張力、剪切和扭矩測(cè)量分析系統(tǒng),Mach-1? Multiaxial Mechanical Testers是1999年推出的力學(xué)測(cè)試系統(tǒng)(圖1),*初用于測(cè)試軟骨,現(xiàn)在可以用于測(cè)試各種組織和軟材料的力學(xué)性質(zhì)。Mach-1體積小,采用模塊化設(shè)計(jì)且可以進(jìn)行定制,在生物材料研究中具有廣泛的應(yīng)用。
系統(tǒng)亮點(diǎn):
l 大范圍高精度多軸測(cè)試:可測(cè)量動(dòng)態(tài)、靜態(tài)和各種波形的壓縮、張力、剪切和扭矩
l 可在標(biāo)準(zhǔn)的培養(yǎng)皿中進(jìn)行力學(xué)刺激實(shí)驗(yàn)
l 用戶友好的數(shù)據(jù)采集和分析軟件
l 可作為理想的教學(xué)工具
l 體積小,方便攜帶
l 可**測(cè)試微米至厘米范圍內(nèi)低力學(xué)性質(zhì)的樣品
Biomentum為提供多種標(biāo)準(zhǔn)和定制的附件來滿足不同的需要。Mach-1可更換壓縮桿對(duì)不同的細(xì)胞進(jìn)行測(cè)量,測(cè)試室和固定裝置也有很多種型號(hào)供客戶選擇。通過這些零件的組合,Mach-1可以對(duì)動(dòng)脈、關(guān)節(jié)軟骨、生物反應(yīng)器、骨、中央神經(jīng)系統(tǒng)、彈性纖維、胎膜、皮膚、水凝膠等材料實(shí)現(xiàn)表面力學(xué)譜測(cè)定(圖2 A)、壓痕實(shí)驗(yàn)(圖2 B)、非受限壓縮實(shí)驗(yàn)(圖2 C)、施加力學(xué)刺激(圖2 D)、肌腱張力測(cè)試(圖2 D)等功能。
Mechanical Testing System - Application Examples
Biomomentum offers a selection of standard and custom-designed accessories. Interchangeable compression rods can be provided with any Mach-1? system, each attached directly to the load cell for application-specific load measurements. A range of testing chambers and fixtures can also be designed and manufactured in adherence with the unique needs of the client. Examples of accessories offered by Biomomentum are depicted below with corresponding applications.
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Indentation on Articular Cartilage
Automated Indentation Mapping
Human (Sim et al., 2014)
Mice (Lavoie et al., 2014)
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Unconfined Compression
Chitosan Thermogel (Coutu et al., 2013)
Swine Growth Plate (Sergerie et al., 2009)
Agarose Gel (Tran-Khanh et al., 2005)
Cartilage Repair Scaffold (Hoemann et al., 2005)
Cartilage (Fortin et al., 2000)
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Mechanical Stimulation
Multi-Axial Mechanical Stimulation (Waldman et al., 2007)
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Tension Testing
Rabbit Patellar Tendon (Clemmer et al., 2010)
Wound Healing
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Mechanical Testing System
The Mach-1? is a mechanical testing system commercially available since 1999. Originally developed for cartilage testing, this multiple-axis tester is now being used in various configurations for the evaluation of mechanical properties of tissues and soft material. Due to its small footprint, modular design and customization features, the Mach-1? offers versatility in numerous biological, biomaterial, and material testing applications.
iomomentum has developed innovative functionalities for Automated Indentation Mapping of articular cartilage samples with the use of the unique multiple-axis capabilities of the Mach-1? V500css.
Mach-1? Models
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V500c
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1 Stage for Compression / Tension Testing
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V500cs
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1 Vertical Stage & 1 Horizontal Stage for Compression / Tension and Shear Testing
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V500ct
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1 Vertical Stage & 1 Rotation Stage for Compression / Tension and Torsion Testing
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V500cst
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1 Vertical, 1 Horizontal & 1 Rotation Stage for Compression / Tension, Shear and Torsion Testing
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V500css
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1 Vertical & 2 Horizontal Stages for Compression / Tension and Shear (along 2 Axes) Testing
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Pitney, M., van Niekerk, E., Dokos, S., Pelletier, M., & Walsh, W. R. (2013). Longitudinal Stent Deformation: Importance of Stent Type and Stent Apposition. American Journal of Biomedical Engineering, 3(3), 63-69. Full Text
Coutu, J.-M. (2012). Influence de l'agent de contraste sur les propriétés du thermogel de chitosane vers un nouvel agent embolisant pour les anévrismes. (Ma?trise), école de technologie supérieure. Abstract
Suen, R. S., Rampersad, S. N., Stewart, D. J., & Courtman, D. W. (2011). Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice. The American journal of pathology, 179(3), 1549-1559. Abstract
Arribas, S. M., Briones, A. M., Bellingham, C., González, M. C., Salaices, M., Liu, K., Wang, Y., Hinek, A. (2008). Heightened aberrant deposition of hard-wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiffness and inward remodeling. Am J Physiol Heart Circ Physiol, 295(6), H2299-2307. Abstract
Iliopoulos, J. (2006). The Aortic Wrap Procedure: A Surgical Method of Treating Age-Related Aortic Dilatation and Stiffness. (PhD), University of New South Wales, Sydney.
Mechanical Testing System - Scientific Publications & Material
Articular Cartilage
S. Sim, A. Chevrier, M. Garon, E. Quenneville and Michael D. Buschmann. Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Early Osteoarthritis-like Regions. Podium presentation ID: 18-5. Annual conference of the European Society for Biomaterials, August 31 - September 3, 2014, Liverpool, UK. Presentation
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Indentation Method to Map Mechanical Properties of Articular Surface to Identify Degenerated Regions. Podium presentation ID: OP-Sat-3-4. Annual Meeting of the Biomedical Engineering Society, October 22-25, 2014, San Antonio, TX, USA. Presentation
J.-F. Lavoie, S. Sim, A. Moreau, C.-é. Aubin, E. Quenneville, M. Garon, and M.D. Bushmann (2014) Mapping Biomechanical Properties of Mice Articular Surfaces Using Indentation: Preliminary Results. Poster ID: P-Th-183.Poster
S. Sim, A. Chevrier, M. Garon, E. Quenneville, and M.D. Buschmann (2014) Novel Technique to Map the Biomechanical Properties of Entire Articular Surfaces Using Indentation to Identify Degenerated (Osteoarthritis-like) Cartilage. Poster 2229. World Congress on Biomechanics, July 6-11, 2014, Boston, MA, USA. Poster